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Case Study 8
No sperm, TESA, IVF-ICSI, twin pregnancy


Mr and Mrs G only decided to become parents after 3 years of marriage. However, they were unsuccessful after two years of trial. They sought medical advice and Mr G was diagnosed as azoospermic (no sperm in the ejaculate).

Mr G was very disappointed but Mrs G was optimistic. She advised her husband to go for further tests to determine the cause and hopefully to find a cure. Further investigations by an urologist showed that it’s a case of obstructive azoospermia due to previous infection. This means that Mr G’s testes are still producing sperm but a blockage in his reproductive tract prevented his sperm from being released in ejaculate. They can still have children of their own but Mr G must first be operated to extract sperm from his testes.

Mrs G, on the other hand, would have to undergo IVF treatment to have her eggs fertilised by ICSI. The extracted sperm was frozen and Mrs G was prepared for an egg collection with daily injection of hormones starting on the second day of her period. 12 eggs were collected and 3 embryos were replaced but C failed to get pregnant. The remaining embryos were not good enough to be frozen.

A second IVF/ICSI attempt was done three months later and Mrs G successfully conceived twin girls using the frozen epididymal sperm. Two beautiful girls were delivered after 37 weeks gestation.


Glossary
IVF
In-vitro fertilisation. A process where sperm are placed together with eggs extracted (by a minor operation) from a woman in the laboratory culture dish to enable fertilisation to take place.
ICSI
Intracytoplasmic sperm injection. A procedure whereby a single sperm is injected into a single egg by means of a very fine needle using micromanipulation techniques.
MESA
Microepididymal sperm aspiration. A microsurgical operation where sperm from the epididymes (part of the testes) are aspirated by a fine needle.
 
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